Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy

Gehan Abdelhaleim Abdelhaleim Ahmed; Elsafi Ahmed Abdalla; Caroline Edward Ayad

doi:doi:10.11648/j.ajhr.20140203.12

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Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy

Gehan Abdelhaleim Abdelhaleim Ahmed, Elsafi Ahmed Abdalla, Caroline Edward Ayad

Published in American Journal of Health Research (Volume 2, Issue 3)

Received: 10 March 2014 Accepted: 16 April 2014 Published: 30 April 2014

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Abstract

This Study aimed to assess the Doppler indices for ophthalmic artery in type 1diabetic pregnant ladies. Inclusion criteria were 15diabetic pregnant ladies, their ages were (30-39), 14 healthy pregnant non diabetic ladies aged (30-37), and 15 healthy non pregnant non diabetic subjects aged (30-41) were selected as control group. Pregnant ladies with eye disease or pregnancy abnormality or preeclampsia were excluded. Ultrasound examination for both eyes were obtained using 7.5MHZ high resolution ultrasound machine. Readings of Ophthalmic artery Doppler indices (resistive index (RI), pulsatility index (PI)) for type 1 diabetes ladies were found to be greater when compared with the control group values and Mean Velocity (MV) was of lower values. The mean values ± SD were as follows: for right eye: resistive index, 1.3 ± 0.2 (P < .005 Control0.8 ± 0.1); pulsatility index, (3.6 ± 0.4 (P < .005Control1.6 ± 0.4); Mean Velocity (MV) 5.2 ± 1.1(P < .005 Control 8.4 ± 3.2). For left eye resistive index, 1.4 ± 0.2 (P < .005 Control 0.7 ± 0.1); pulsatility index, 3.3 ± 0.5 (P < .005Control 1.6 ± 0.3); Mean Velocity (MV) 5.7 ± 0.8 (P < .005 Control 8.5 ± 3.2). The correlations between the variables and gestational age in the two pregnant groups were studied and were compared with the control group and maternal treatment. The study revealed that the Doppler indices for right and left eyes differed significantly within the three trimesters for pregnant diabetic and pregnant non diabetic ladies and when compared with the control group at p-value ˂0.05. No significant difference was detected between the Doppler indices and the treatment taken as Diet Control, or insulin for type 1 diabetic pregnant ladies. Color Doppler Ultrasonography is useful for assessing blood flow. Ophthalmic arteries Doppler Indices were affected significantly in pregnant ladies with or without type 1diabetes.

Published in	American Journal of Health Research (Volume 2, Issue 3)
DOI	10.11648/j.ajhr.20140203.12
Page(s)	89-92
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Type 1 Diabetes, Pregnancy, Doppler Ultrasonography

References

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[6]	R.S .Carneiro, N. Sass, A.L. Diniz, E.V. Souza, M.R. Torloni, A.F. Moron. Ophthalmic artery Doppler velocimetry in health pregnancy. In J Gynaecol Obstet 2008; 100:211–215
[7]	F .Mackenzie, R. De Vermette, C .Nimrod, D .Boisvert, B .Jackson. Doppler sonographic studies on the ophthalmic and central retinal arteries in the gravid woman. J Ultrasound Med 1995; 14:643–647 (references)
[8]	Y. Ohno, M. Kawai, Y .Wakahara, T .Kitagawa, M .Kakihara, Y. Arii. Ophthalmic artery velocimetry in normotensive and preeclamptic women with or without photophobia. Obstet Gynecol 1999; 94:361–363.
[9]	R.S .Tompson, B.J .Trudinger, C.M. Cook. Doppler ultrasound waveform in-dices: A/B ratio, pulsatility index and Porcelot ratio. Br J Obstet Gynaecol 1988; 95:581–588
[10]	A.L. Diniz, A.F .Moron, M.C .Santos, C.R. Pires. Doppler velocimetria das artérias oftálmica e central da retina em gestantes normais. Rev Bras GinecolObstet 2005; 27: 168–173.
[11]	F .Mackenzie, R .De Vermette, C. Nimrod, D. Boisvert, B. Jackson. Doppler so-nographic studies on the ophthalmic and central retinal arteries in the gravid woman. J Ultra-sound Med 1995; 14:643–647
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[14]	T .Kawagishi, Y .Nishizawa, M .Emoto, T .Konishi, K .Maekawa, S .Hagiwara, Y .Okuno, H .Inada, G .Isshiki, H. Morii. Impaired retinal artery blood flow in IDDM patients before clinical manifestations of diabetic retinopathy. Diabetes Care 1995;18:1544–1549
[15]	G.T .Feke, S.M .Buzney, H. Ogasawara, N.Fujio, D.G. Goger, N.P. Spack, K.H .Gabbay. Retinal circulatory abnormalities in type 1 diabetes. Invest Ophthalmol Vis Sci 1994; 35: 2968–2975
[16]	K.L .Thornburg, S-L .Jacobson, G.D .Giraud, M.J. Morton. Hemodynamic changes in pregnancy. Semin Perinatol. 2000; 24:11–14.
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APA Style

Gehan Abdelhaleim Abdelhaleim Ahmed, Elsafi Ahmed Abdalla, Caroline Edward Ayad. (2014). Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy. American Journal of Health Research, 2(3), 89-92. https://doi.org/10.11648/j.ajhr.20140203.12

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ACS Style

Gehan Abdelhaleim Abdelhaleim Ahmed; Elsafi Ahmed Abdalla; Caroline Edward Ayad. Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy. Am. J. Health Res. 2014, 2(3), 89-92. doi: 10.11648/j.ajhr.20140203.12

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AMA Style

Gehan Abdelhaleim Abdelhaleim Ahmed, Elsafi Ahmed Abdalla, Caroline Edward Ayad. Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy. Am J Health Res. 2014;2(3):89-92. doi: 10.11648/j.ajhr.20140203.12

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@article{10.11648/j.ajhr.20140203.12,
  author = {Gehan Abdelhaleim Abdelhaleim Ahmed and Elsafi Ahmed Abdalla and Caroline Edward Ayad},
  title = {Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy},
  journal = {American Journal of Health Research},
  volume = {2},
  number = {3},
  pages = {89-92},
  doi = {10.11648/j.ajhr.20140203.12},
  url = {https://doi.org/10.11648/j.ajhr.20140203.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20140203.12},
  abstract = {This Study aimed to assess the Doppler indices for ophthalmic artery in type 1diabetic pregnant ladies. Inclusion criteria were 15diabetic pregnant ladies, their ages were (30-39), 14 healthy pregnant non diabetic ladies aged (30-37), and 15 healthy non pregnant non diabetic subjects aged (30-41) were selected as control group. Pregnant ladies with eye disease or pregnancy abnormality or preeclampsia were excluded. Ultrasound examination for both eyes were obtained using 7.5MHZ high resolution ultrasound machine. Readings of Ophthalmic artery Doppler indices (resistive index (RI), pulsatility index (PI)) for type 1 diabetes ladies were found to be greater when compared with the control group values and Mean Velocity (MV) was of lower values. The mean values ± SD were as follows: for right eye: resistive index, 1.3 ± 0.2 (P < .005 Control0.8 ± 0.1); pulsatility index, (3.6 ± 0.4 (P < .005Control1.6 ± 0.4); Mean Velocity (MV) 5.2 ± 1.1(P < .005 Control 8.4 ± 3.2). For left eye resistive index, 1.4 ± 0.2 (P < .005 Control 0.7 ± 0.1); pulsatility index, 3.3 ± 0.5 (P < .005Control 1.6 ± 0.3); Mean Velocity (MV) 5.7 ± 0.8 (P < .005 Control 8.5 ± 3.2). The correlations between the variables and gestational age in the two pregnant groups were studied and were compared with the control group and maternal treatment. The study revealed that the Doppler indices for right and left eyes differed significantly within the three trimesters for pregnant diabetic and pregnant non diabetic ladies and when compared with the control group at p-value ˂0.05. No significant difference was detected between the Doppler indices and the treatment taken as Diet Control, or insulin for type 1 diabetic pregnant ladies. Color Doppler Ultrasonography is useful for assessing blood flow. Ophthalmic arteries Doppler Indices were affected significantly in pregnant ladies with or without type 1diabetes.},
 year = {2014}
}

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TY  - JOUR
T1  - Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy
AU  - Gehan Abdelhaleim Abdelhaleim Ahmed
AU  - Elsafi Ahmed Abdalla
AU  - Caroline Edward Ayad
Y1  - 2014/04/30
PY  - 2014
N1  - https://doi.org/10.11648/j.ajhr.20140203.12
DO  - 10.11648/j.ajhr.20140203.12
T2  - American Journal of Health Research
JF  - American Journal of Health Research
JO  - American Journal of Health Research
SP  - 89
EP  - 92
PB  - Science Publishing Group
SN  - 2330-8796
UR  - https://doi.org/10.11648/j.ajhr.20140203.12
AB  - This Study aimed to assess the Doppler indices for ophthalmic artery in type 1diabetic pregnant ladies. Inclusion criteria were 15diabetic pregnant ladies, their ages were (30-39), 14 healthy pregnant non diabetic ladies aged (30-37), and 15 healthy non pregnant non diabetic subjects aged (30-41) were selected as control group. Pregnant ladies with eye disease or pregnancy abnormality or preeclampsia were excluded. Ultrasound examination for both eyes were obtained using 7.5MHZ high resolution ultrasound machine. Readings of Ophthalmic artery Doppler indices (resistive index (RI), pulsatility index (PI)) for type 1 diabetes ladies were found to be greater when compared with the control group values and Mean Velocity (MV) was of lower values. The mean values ± SD were as follows: for right eye: resistive index, 1.3 ± 0.2 (P < .005 Control0.8 ± 0.1); pulsatility index, (3.6 ± 0.4 (P < .005Control1.6 ± 0.4); Mean Velocity (MV) 5.2 ± 1.1(P < .005 Control 8.4 ± 3.2). For left eye resistive index, 1.4 ± 0.2 (P < .005 Control 0.7 ± 0.1); pulsatility index, 3.3 ± 0.5 (P < .005Control 1.6 ± 0.3); Mean Velocity (MV) 5.7 ± 0.8 (P < .005 Control 8.5 ± 3.2). The correlations between the variables and gestational age in the two pregnant groups were studied and were compared with the control group and maternal treatment. The study revealed that the Doppler indices for right and left eyes differed significantly within the three trimesters for pregnant diabetic and pregnant non diabetic ladies and when compared with the control group at p-value ˂0.05. No significant difference was detected between the Doppler indices and the treatment taken as Diet Control, or insulin for type 1 diabetic pregnant ladies. Color Doppler Ultrasonography is useful for assessing blood flow. Ophthalmic arteries Doppler Indices were affected significantly in pregnant ladies with or without type 1diabetes.
VL  - 2
IS  - 3
ER  -

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Author Information

Gehan Abdelhaleim Abdelhaleim Ahmed

Radiology Department, Sudan University of Science and Technology, College of Medical Radiological Science, Khartoum, Sudan
Elsafi Ahmed Abdalla

Radiology Department, Sudan University of Science and Technology, College of Medical Radiological Science, Khartoum, Sudan
Caroline Edward Ayad

Radiology Department, Sudan University of Science and Technology, College of Medical Radiological Science, Khartoum, Sudan

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APA Style

Gehan Abdelhaleim Abdelhaleim Ahmed, Elsafi Ahmed Abdalla, Caroline Edward Ayad. (2014). Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy. American Journal of Health Research, 2(3), 89-92. https://doi.org/10.11648/j.ajhr.20140203.12

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ACS Style

Gehan Abdelhaleim Abdelhaleim Ahmed; Elsafi Ahmed Abdalla; Caroline Edward Ayad. Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy. Am. J. Health Res. 2014, 2(3), 89-92. doi: 10.11648/j.ajhr.20140203.12

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AMA Style

Gehan Abdelhaleim Abdelhaleim Ahmed, Elsafi Ahmed Abdalla, Caroline Edward Ayad. Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy. Am J Health Res. 2014;2(3):89-92. doi: 10.11648/j.ajhr.20140203.12

Copy | Download

@article{10.11648/j.ajhr.20140203.12,
  author = {Gehan Abdelhaleim Abdelhaleim Ahmed and Elsafi Ahmed Abdalla and Caroline Edward Ayad},
  title = {Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy},
  journal = {American Journal of Health Research},
  volume = {2},
  number = {3},
  pages = {89-92},
  doi = {10.11648/j.ajhr.20140203.12},
  url = {https://doi.org/10.11648/j.ajhr.20140203.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20140203.12},
  abstract = {This Study aimed to assess the Doppler indices for ophthalmic artery in type 1diabetic pregnant ladies. Inclusion criteria were 15diabetic pregnant ladies, their ages were (30-39), 14 healthy pregnant non diabetic ladies aged (30-37), and 15 healthy non pregnant non diabetic subjects aged (30-41) were selected as control group. Pregnant ladies with eye disease or pregnancy abnormality or preeclampsia were excluded. Ultrasound examination for both eyes were obtained using 7.5MHZ high resolution ultrasound machine. Readings of Ophthalmic artery Doppler indices (resistive index (RI), pulsatility index (PI)) for type 1 diabetes ladies were found to be greater when compared with the control group values and Mean Velocity (MV) was of lower values. The mean values ± SD were as follows: for right eye: resistive index, 1.3 ± 0.2 (P < .005 Control0.8 ± 0.1); pulsatility index, (3.6 ± 0.4 (P < .005Control1.6 ± 0.4); Mean Velocity (MV) 5.2 ± 1.1(P < .005 Control 8.4 ± 3.2). For left eye resistive index, 1.4 ± 0.2 (P < .005 Control 0.7 ± 0.1); pulsatility index, 3.3 ± 0.5 (P < .005Control 1.6 ± 0.3); Mean Velocity (MV) 5.7 ± 0.8 (P < .005 Control 8.5 ± 3.2). The correlations between the variables and gestational age in the two pregnant groups were studied and were compared with the control group and maternal treatment. The study revealed that the Doppler indices for right and left eyes differed significantly within the three trimesters for pregnant diabetic and pregnant non diabetic ladies and when compared with the control group at p-value ˂0.05. No significant difference was detected between the Doppler indices and the treatment taken as Diet Control, or insulin for type 1 diabetic pregnant ladies. Color Doppler Ultrasonography is useful for assessing blood flow. Ophthalmic arteries Doppler Indices were affected significantly in pregnant ladies with or without type 1diabetes.},
 year = {2014}
}

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TY  - JOUR
T1  - Maternal Ophthalmic Artery Doppler Indices in Type 1 Diabetes during Pregnancy
AU  - Gehan Abdelhaleim Abdelhaleim Ahmed
AU  - Elsafi Ahmed Abdalla
AU  - Caroline Edward Ayad
Y1  - 2014/04/30
PY  - 2014
N1  - https://doi.org/10.11648/j.ajhr.20140203.12
DO  - 10.11648/j.ajhr.20140203.12
T2  - American Journal of Health Research
JF  - American Journal of Health Research
JO  - American Journal of Health Research
SP  - 89
EP  - 92
PB  - Science Publishing Group
SN  - 2330-8796
UR  - https://doi.org/10.11648/j.ajhr.20140203.12
AB  - This Study aimed to assess the Doppler indices for ophthalmic artery in type 1diabetic pregnant ladies. Inclusion criteria were 15diabetic pregnant ladies, their ages were (30-39), 14 healthy pregnant non diabetic ladies aged (30-37), and 15 healthy non pregnant non diabetic subjects aged (30-41) were selected as control group. Pregnant ladies with eye disease or pregnancy abnormality or preeclampsia were excluded. Ultrasound examination for both eyes were obtained using 7.5MHZ high resolution ultrasound machine. Readings of Ophthalmic artery Doppler indices (resistive index (RI), pulsatility index (PI)) for type 1 diabetes ladies were found to be greater when compared with the control group values and Mean Velocity (MV) was of lower values. The mean values ± SD were as follows: for right eye: resistive index, 1.3 ± 0.2 (P < .005 Control0.8 ± 0.1); pulsatility index, (3.6 ± 0.4 (P < .005Control1.6 ± 0.4); Mean Velocity (MV) 5.2 ± 1.1(P < .005 Control 8.4 ± 3.2). For left eye resistive index, 1.4 ± 0.2 (P < .005 Control 0.7 ± 0.1); pulsatility index, 3.3 ± 0.5 (P < .005Control 1.6 ± 0.3); Mean Velocity (MV) 5.7 ± 0.8 (P < .005 Control 8.5 ± 3.2). The correlations between the variables and gestational age in the two pregnant groups were studied and were compared with the control group and maternal treatment. The study revealed that the Doppler indices for right and left eyes differed significantly within the three trimesters for pregnant diabetic and pregnant non diabetic ladies and when compared with the control group at p-value ˂0.05. No significant difference was detected between the Doppler indices and the treatment taken as Diet Control, or insulin for type 1 diabetic pregnant ladies. Color Doppler Ultrasonography is useful for assessing blood flow. Ophthalmic arteries Doppler Indices were affected significantly in pregnant ladies with or without type 1diabetes.
VL  - 2
IS  - 3
ER  -

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