Side Effects of Non-Steroidal Anti-Inflammatory Drugs: The Experience of Patients with Musculoskeletal Disorders

Onigbinde Ayodele Teslim; M’Kumbuzi Vyvienne; Olaogun Mathew Olatokunbo; Afolabi Joshua Oluwafisayo; Nondwe Bongokazi Mlenzana; Manie Shamila; Tarimo Nesto; Mukoka Grace

doi:doi:10.11648/j.ajhr.20140204.11

Side Effects of Non-Steroidal Anti-Inflammatory Drugs: The Experience of Patients with Musculoskeletal Disorders

Onigbinde Ayodele Teslim, M’Kumbuzi Vyvienne, Olaogun Mathew Olatokunbo, Afolabi Joshua Oluwafisayo, Nondwe Bongokazi Mlenzana, Manie Shamila, Tarimo Nesto, Mukoka Grace

Published in American Journal of Health Research (Volume 2, Issue 4)

Received: 25 June 2014 Accepted: 10 July 2014 Published: 20 July 2014

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Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are of choice for acute pain management in musculoskeletal disorders (MSDs) but they are not without side effects. The primary aim of this study was to investigate user’s experience of side effects of oral NSAIDs among patients with MSDs. Multi-stage sampling technique was used to select 296 patients with MSDs from physiotherapy out-patient clinics of five selected hospitals. A structured and close ended questionnaire was administered to investigate the side effects experienced by respondents. Descriptive statistics (mean, standard deviation, frequency and percentages) and Chi-square were used to compare the mean percentage difference in the knowledge of NSAIDs and their side effects. Only 15% of the respondents were able to recognize the listed side effects. A significant number of the respondents (58.7%) were not informed of the side effects of the NSAIDs at the time of prescription (Ӽ2 = 8.82, p = 0.003). About 33.4% and 31% of respondents identified dizziness and abdominal pain respectively as side effects. Sixty two (22.3%) respondents had experienced dizziness while 15.9% experienced abdominal pains. Diclofenac was the most frequently prescribed NSAID (153 [51.7%]). Only 2.0% and 2.7% of respondents were aware of phonophoresis and iontophoresis respectively as alternative means of administering NSAIDs where applicable. The Chi-square test revealed that the number of respondents that preferred alternative means of administration (where applicable) was significantly higher than those who preferred the oral routes (x2 = 74.5, p = 0.001). We concluded that this sample of Nigerian patients was not informed of the side effects of NSAIDs by the prescribers. Dizziness and abdominal pains were the most experienced side effects. The role of alternative methods to administer NSAIDs need to be made available to patients where applicable to increase their health care choices.

Published in	American Journal of Health Research (Volume 2, Issue 4)
DOI	10.11648/j.ajhr.20140204.11
Page(s)	106-112
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Side Effects, Non-Steroidal Anti-Inflammatory Drugs, Patient’s Experience, Musculoskeletal Disorders

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Onigbinde Ayodele Teslim, M’Kumbuzi Vyvienne, Olaogun Mathew Olatokunbo, Afolabi Joshua Oluwafisayo, Nondwe Bongokazi Mlenzana, et al. (2014). Side Effects of Non-Steroidal Anti-Inflammatory Drugs: The Experience of Patients with Musculoskeletal Disorders. American Journal of Health Research, 2(4), 106-112. https://doi.org/10.11648/j.ajhr.20140204.11

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ACS Style

Onigbinde Ayodele Teslim; M’Kumbuzi Vyvienne; Olaogun Mathew Olatokunbo; Afolabi Joshua Oluwafisayo; Nondwe Bongokazi Mlenzana, et al. Side Effects of Non-Steroidal Anti-Inflammatory Drugs: The Experience of Patients with Musculoskeletal Disorders. Am. J. Health Res. 2014, 2(4), 106-112. doi: 10.11648/j.ajhr.20140204.11

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AMA Style

Onigbinde Ayodele Teslim, M’Kumbuzi Vyvienne, Olaogun Mathew Olatokunbo, Afolabi Joshua Oluwafisayo, Nondwe Bongokazi Mlenzana, et al. Side Effects of Non-Steroidal Anti-Inflammatory Drugs: The Experience of Patients with Musculoskeletal Disorders. Am J Health Res. 2014;2(4):106-112. doi: 10.11648/j.ajhr.20140204.11

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@article{10.11648/j.ajhr.20140204.11,
  author = {Onigbinde Ayodele Teslim and M’Kumbuzi Vyvienne and Olaogun Mathew Olatokunbo and Afolabi Joshua Oluwafisayo and Nondwe Bongokazi Mlenzana and Manie Shamila and Tarimo Nesto and Mukoka Grace},
  title = {Side Effects of Non-Steroidal Anti-Inflammatory Drugs: The Experience of Patients with Musculoskeletal Disorders},
  journal = {American Journal of Health Research},
  volume = {2},
  number = {4},
  pages = {106-112},
  doi = {10.11648/j.ajhr.20140204.11},
  url = {https://doi.org/10.11648/j.ajhr.20140204.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20140204.11},
  abstract = {Non-steroidal anti-inflammatory drugs (NSAIDs) are of choice for acute pain management in musculoskeletal disorders (MSDs) but they are not without side effects. The primary aim of this study was to investigate user’s experience of side effects of oral NSAIDs among patients with MSDs. Multi-stage sampling technique was used to select 296 patients with MSDs from physiotherapy out-patient clinics of five selected hospitals. A structured and close ended questionnaire was administered to investigate the side effects experienced by respondents. Descriptive statistics (mean, standard deviation, frequency and percentages) and Chi-square were used to compare the mean percentage difference in the knowledge of NSAIDs and their side effects. Only 15% of the respondents were able to recognize the listed side effects. A significant number of the respondents (58.7%) were not informed of the side effects of the NSAIDs at the time of prescription (Ӽ2 = 8.82, p = 0.003). About 33.4% and 31% of respondents identified dizziness and abdominal pain respectively as side effects. Sixty two (22.3%) respondents had experienced dizziness while 15.9% experienced abdominal pains. Diclofenac was the most frequently prescribed NSAID (153 [51.7%]). Only 2.0% and 2.7% of respondents were aware of phonophoresis and iontophoresis respectively as alternative means of administering NSAIDs where applicable. The Chi-square test revealed that the number of respondents that preferred alternative means of administration (where applicable) was significantly higher than those who preferred the oral routes (x2 = 74.5, p = 0.001).  We concluded that this sample of Nigerian patients was not informed of the side effects of NSAIDs by the prescribers. Dizziness and abdominal pains were the most experienced side effects. The role of alternative methods to administer NSAIDs need to be made available to patients where applicable to increase their health care choices.},
 year = {2014}
}

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TY - JOUR
T1 - Side Effects of Non-Steroidal Anti-Inflammatory Drugs: The Experience of Patients with Musculoskeletal Disorders
AU - Onigbinde Ayodele Teslim
AU - M’Kumbuzi Vyvienne
AU - Olaogun Mathew Olatokunbo
AU - Afolabi Joshua Oluwafisayo
AU - Nondwe Bongokazi Mlenzana
AU - Manie Shamila
AU - Tarimo Nesto
AU - Mukoka Grace
Y1 - 2014/07/20
PY - 2014
N1 - https://doi.org/10.11648/j.ajhr.20140204.11
DO - 10.11648/j.ajhr.20140204.11
T2 - American Journal of Health Research
JF - American Journal of Health Research
JO - American Journal of Health Research
SP - 106
EP - 112
PB - Science Publishing Group
SN - 2330-8796
UR - https://doi.org/10.11648/j.ajhr.20140204.11
AB - Non-steroidal anti-inflammatory drugs (NSAIDs) are of choice for acute pain management in musculoskeletal disorders (MSDs) but they are not without side effects. The primary aim of this study was to investigate user’s experience of side effects of oral NSAIDs among patients with MSDs. Multi-stage sampling technique was used to select 296 patients with MSDs from physiotherapy out-patient clinics of five selected hospitals. A structured and close ended questionnaire was administered to investigate the side effects experienced by respondents. Descriptive statistics (mean, standard deviation, frequency and percentages) and Chi-square were used to compare the mean percentage difference in the knowledge of NSAIDs and their side effects. Only 15% of the respondents were able to recognize the listed side effects. A significant number of the respondents (58.7%) were not informed of the side effects of the NSAIDs at the time of prescription (Ӽ2 = 8.82, p = 0.003). About 33.4% and 31% of respondents identified dizziness and abdominal pain respectively as side effects. Sixty two (22.3%) respondents had experienced dizziness while 15.9% experienced abdominal pains. Diclofenac was the most frequently prescribed NSAID (153 [51.7%]). Only 2.0% and 2.7% of respondents were aware of phonophoresis and iontophoresis respectively as alternative means of administering NSAIDs where applicable. The Chi-square test revealed that the number of respondents that preferred alternative means of administration (where applicable) was significantly higher than those who preferred the oral routes (x2 = 74.5, p = 0.001). We concluded that this sample of Nigerian patients was not informed of the side effects of NSAIDs by the prescribers. Dizziness and abdominal pains were the most experienced side effects. The role of alternative methods to administer NSAIDs need to be made available to patients where applicable to increase their health care choices.
VL - 2
IS - 4
ER -

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Author Information

Onigbinde Ayodele Teslim

Department of Medical Rehabilitation, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria
M’Kumbuzi Vyvienne

Department of Physiotherapy, College of Medicine, University of Malawi, Blantyre, Malawi
Olaogun Mathew Olatokunbo

Department of Medical Rehabilitation, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria
Afolabi Joshua Oluwafisayo

Department of Medical Rehabilitation, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria
Nondwe Bongokazi Mlenzana

Department of Physiotherapy, University of the Western Cape, Bellville, South Africa
Manie Shamila

Department of Health and Rehabilitation Science, Faculty of Health Sciences, University Cape Town, Cape Town, South Africa
Tarimo Nesto

Rehabilitation Technician School, Malawi Against Physical Disabilities, P.O.Box 256, Blantyre, Malawi
Mukoka Grace

Department of Physiotherapy, College of Medicine, University of Malawi, Blantyre, Malawi

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Onigbinde Ayodele Teslim, M’Kumbuzi Vyvienne, Olaogun Mathew Olatokunbo, Afolabi Joshua Oluwafisayo, Nondwe Bongokazi Mlenzana, et al. (2014). Side Effects of Non-Steroidal Anti-Inflammatory Drugs: The Experience of Patients with Musculoskeletal Disorders. American Journal of Health Research, 2(4), 106-112. https://doi.org/10.11648/j.ajhr.20140204.11

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ACS Style

Onigbinde Ayodele Teslim; M’Kumbuzi Vyvienne; Olaogun Mathew Olatokunbo; Afolabi Joshua Oluwafisayo; Nondwe Bongokazi Mlenzana, et al. Side Effects of Non-Steroidal Anti-Inflammatory Drugs: The Experience of Patients with Musculoskeletal Disorders. Am. J. Health Res. 2014, 2(4), 106-112. doi: 10.11648/j.ajhr.20140204.11

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AMA Style

Onigbinde Ayodele Teslim, M’Kumbuzi Vyvienne, Olaogun Mathew Olatokunbo, Afolabi Joshua Oluwafisayo, Nondwe Bongokazi Mlenzana, et al. Side Effects of Non-Steroidal Anti-Inflammatory Drugs: The Experience of Patients with Musculoskeletal Disorders. Am J Health Res. 2014;2(4):106-112. doi: 10.11648/j.ajhr.20140204.11

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@article{10.11648/j.ajhr.20140204.11,
  author = {Onigbinde Ayodele Teslim and M’Kumbuzi Vyvienne and Olaogun Mathew Olatokunbo and Afolabi Joshua Oluwafisayo and Nondwe Bongokazi Mlenzana and Manie Shamila and Tarimo Nesto and Mukoka Grace},
  title = {Side Effects of Non-Steroidal Anti-Inflammatory Drugs: The Experience of Patients with Musculoskeletal Disorders},
  journal = {American Journal of Health Research},
  volume = {2},
  number = {4},
  pages = {106-112},
  doi = {10.11648/j.ajhr.20140204.11},
  url = {https://doi.org/10.11648/j.ajhr.20140204.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20140204.11},
  abstract = {Non-steroidal anti-inflammatory drugs (NSAIDs) are of choice for acute pain management in musculoskeletal disorders (MSDs) but they are not without side effects. The primary aim of this study was to investigate user’s experience of side effects of oral NSAIDs among patients with MSDs. Multi-stage sampling technique was used to select 296 patients with MSDs from physiotherapy out-patient clinics of five selected hospitals. A structured and close ended questionnaire was administered to investigate the side effects experienced by respondents. Descriptive statistics (mean, standard deviation, frequency and percentages) and Chi-square were used to compare the mean percentage difference in the knowledge of NSAIDs and their side effects. Only 15% of the respondents were able to recognize the listed side effects. A significant number of the respondents (58.7%) were not informed of the side effects of the NSAIDs at the time of prescription (Ӽ2 = 8.82, p = 0.003). About 33.4% and 31% of respondents identified dizziness and abdominal pain respectively as side effects. Sixty two (22.3%) respondents had experienced dizziness while 15.9% experienced abdominal pains. Diclofenac was the most frequently prescribed NSAID (153 [51.7%]). Only 2.0% and 2.7% of respondents were aware of phonophoresis and iontophoresis respectively as alternative means of administering NSAIDs where applicable. The Chi-square test revealed that the number of respondents that preferred alternative means of administration (where applicable) was significantly higher than those who preferred the oral routes (x2 = 74.5, p = 0.001).  We concluded that this sample of Nigerian patients was not informed of the side effects of NSAIDs by the prescribers. Dizziness and abdominal pains were the most experienced side effects. The role of alternative methods to administer NSAIDs need to be made available to patients where applicable to increase their health care choices.},
 year = {2014}
}

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