Vitex Nigundo Linn. is credited with important medicinal activities such as antioxidant, anti-inflammatory, analgesic, anticonvulsant etc. The purpose of the presents study was to assess the therapy effect of V. Nigundo leaves extract on glucose level, total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, SGPT and SGOT in blood serum of diabetic animals. Ethyl alcohol extract of V. Nigundo leaves in doses of 200 and 300 mgkg-1 body weights was daily administered orally by gavages to mice for 21 days to evaluate their antihyperglycemic and antihyperlipidemic effects on normal and streptozotocin-induced diabetic mice. Ethyl alcohol extract of V. Nigundo leaves in doses of 300 mgkg-1 body weights showed (P<0.01) more significant activity than the ethyl alcohol extract of V. Nigundo leaves in doses of 200 mgkg-1 body weights. The study validates scientifically the widely claimed use of V. Nigundo leaves as an ethnomedicine to treat diabetes mellitus.
| Published in | American Journal of Life Sciences (Volume 5, Issue 1) |
| DOI | 10.11648/j.ajls.20170501.14 |
| Page(s) | 21-26 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2017. Published by Science Publishing Group |
Vitex nigundo, Antidiabetic, Diabetes Mellitus, Hyperglycemic, Hyperlipidemic
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APA Style
Most. Fatimatuz Zahura Falguni, Md. Amirul Islam, Md. Mahmudul Hasan, S. M. M. Mahmud Hossain Mousum, Md. Ashraduzzaman, et al. (2017). Antioxidant and Antidiabetic Properties of Vitex nigundo L. Leaves. American Journal of Life Sciences, 5(1), 21-26. https://doi.org/10.11648/j.ajls.20170501.14
ACS Style
Most. Fatimatuz Zahura Falguni; Md. Amirul Islam; Md. Mahmudul Hasan; S. M. M. Mahmud Hossain Mousum; Md. Ashraduzzaman, et al. Antioxidant and Antidiabetic Properties of Vitex nigundo L. Leaves. Am. J. Life Sci. 2017, 5(1), 21-26. doi: 10.11648/j.ajls.20170501.14
AMA Style
Most. Fatimatuz Zahura Falguni, Md. Amirul Islam, Md. Mahmudul Hasan, S. M. M. Mahmud Hossain Mousum, Md. Ashraduzzaman, et al. Antioxidant and Antidiabetic Properties of Vitex nigundo L. Leaves. Am J Life Sci. 2017;5(1):21-26. doi: 10.11648/j.ajls.20170501.14
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Download@article{10.11648/j.ajls.20170501.14,
author = {Most. Fatimatuz Zahura Falguni and Md. Amirul Islam and Md. Mahmudul Hasan and S. M. M. Mahmud Hossain Mousum and Md. Ashraduzzaman and Shahanaz Khatun},
title = {Antioxidant and Antidiabetic Properties of Vitex nigundo L. Leaves},
journal = {American Journal of Life Sciences},
volume = {5},
number = {1},
pages = {21-26},
doi = {10.11648/j.ajls.20170501.14},
url = {https://doi.org/10.11648/j.ajls.20170501.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20170501.14},
abstract = {Vitex Nigundo Linn. is credited with important medicinal activities such as antioxidant, anti-inflammatory, analgesic, anticonvulsant etc. The purpose of the presents study was to assess the therapy effect of V. Nigundo leaves extract on glucose level, total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, SGPT and SGOT in blood serum of diabetic animals. Ethyl alcohol extract of V. Nigundo leaves in doses of 200 and 300 mgkg-1 body weights was daily administered orally by gavages to mice for 21 days to evaluate their antihyperglycemic and antihyperlipidemic effects on normal and streptozotocin-induced diabetic mice. Ethyl alcohol extract of V. Nigundo leaves in doses of 300 mgkg-1 body weights showed (P<0.01) more significant activity than the ethyl alcohol extract of V. Nigundo leaves in doses of 200 mgkg-1 body weights. The study validates scientifically the widely claimed use of V. Nigundo leaves as an ethnomedicine to treat diabetes mellitus.},
year = {2017}
}
TY - JOUR T1 - Antioxidant and Antidiabetic Properties of Vitex nigundo L. Leaves AU - Most. Fatimatuz Zahura Falguni AU - Md. Amirul Islam AU - Md. Mahmudul Hasan AU - S. M. M. Mahmud Hossain Mousum AU - Md. Ashraduzzaman AU - Shahanaz Khatun Y1 - 2017/03/06 PY - 2017 N1 - https://doi.org/10.11648/j.ajls.20170501.14 DO - 10.11648/j.ajls.20170501.14 T2 - American Journal of Life Sciences JF - American Journal of Life Sciences JO - American Journal of Life Sciences SP - 21 EP - 26 PB - Science Publishing Group SN - 2328-5737 UR - https://doi.org/10.11648/j.ajls.20170501.14 AB - Vitex Nigundo Linn. is credited with important medicinal activities such as antioxidant, anti-inflammatory, analgesic, anticonvulsant etc. The purpose of the presents study was to assess the therapy effect of V. Nigundo leaves extract on glucose level, total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, SGPT and SGOT in blood serum of diabetic animals. Ethyl alcohol extract of V. Nigundo leaves in doses of 200 and 300 mgkg-1 body weights was daily administered orally by gavages to mice for 21 days to evaluate their antihyperglycemic and antihyperlipidemic effects on normal and streptozotocin-induced diabetic mice. Ethyl alcohol extract of V. Nigundo leaves in doses of 300 mgkg-1 body weights showed (P<0.01) more significant activity than the ethyl alcohol extract of V. Nigundo leaves in doses of 200 mgkg-1 body weights. The study validates scientifically the widely claimed use of V. Nigundo leaves as an ethnomedicine to treat diabetes mellitus. VL - 5 IS - 1 ER -
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