Objective: Benign breast disease includes a wide spectrum of lesions different for histology and natural history, whose association with oral contraceptives is of great interest because there are no univocal results in literature. Subjects and Methods: The purpose of our study is to assess the relationship between women who used long- term estro-progestin (for at least 12 consecutive months up to a maximum of 60 months) and the develop of benign breast disease comparing with a case- control group composed by patients with benign breast disease, non-users of oral contraceptives. The study included 263 women attending, from 2009 to 2012, the Gynecological Endocrinology and Ultrasounds outpatients of our Department, who used oestroprogestative pills for Contraception, treatment of acne, hirsutism and treatment of dysmenorrheal and a control group of 200 patients with benign breast disease, non-users of Oral Contraceptives.Results: According to recent trials we did not observe statistically significant morphological and anatomical alterations of the breast in the group treated with estrogen-progestin therapy in comparison with the control group. Conclusion: If the woman presents a nodular breast mass during estro-progestin therapy she should be evaluated ultrasonographically to assess if the formation grows. If there is an increase in volume of the mass the patient should suspend the therapy.
Published in | American Journal of Nursing Science (Volume 1, Issue 1) |
DOI | 10.11648/j.ajns.20120101.11 |
Page(s) | 1-4 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2012. Published by Science Publishing Group |
Oral Contraception, Benign Breast Disease, Breast Cancer, Ultrasound Examination
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APA Style
A. Carbonaro, L. Ciotta, M. Stracquadanio, C. Formuso, M. R. Giunta, et al. (2012). Oral Contraception and Breast Diseases. American Journal of Nursing Science, 1(1), 1-4. https://doi.org/10.11648/j.ajns.20120101.11
ACS Style
A. Carbonaro; L. Ciotta; M. Stracquadanio; C. Formuso; M. R. Giunta, et al. Oral Contraception and Breast Diseases. Am. J. Nurs. Sci. 2012, 1(1), 1-4. doi: 10.11648/j.ajns.20120101.11
AMA Style
A. Carbonaro, L. Ciotta, M. Stracquadanio, C. Formuso, M. R. Giunta, et al. Oral Contraception and Breast Diseases. Am J Nurs Sci. 2012;1(1):1-4. doi: 10.11648/j.ajns.20120101.11
@article{10.11648/j.ajns.20120101.11, author = {A. Carbonaro and L. Ciotta and M. Stracquadanio and C. Formuso and M. R. Giunta and A. D. Agati and V. Leanza and T. T. Giannone and Mayada Chammas and Fawzi Chammas and C. Pafumi and G. Zarbo}, title = {Oral Contraception and Breast Diseases}, journal = {American Journal of Nursing Science}, volume = {1}, number = {1}, pages = {1-4}, doi = {10.11648/j.ajns.20120101.11}, url = {https://doi.org/10.11648/j.ajns.20120101.11}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajns.20120101.11}, abstract = {Objective: Benign breast disease includes a wide spectrum of lesions different for histology and natural history, whose association with oral contraceptives is of great interest because there are no univocal results in literature. Subjects and Methods: The purpose of our study is to assess the relationship between women who used long- term estro-progestin (for at least 12 consecutive months up to a maximum of 60 months) and the develop of benign breast disease comparing with a case- control group composed by patients with benign breast disease, non-users of oral contraceptives. The study included 263 women attending, from 2009 to 2012, the Gynecological Endocrinology and Ultrasounds outpatients of our Department, who used oestroprogestative pills for Contraception, treatment of acne, hirsutism and treatment of dysmenorrheal and a control group of 200 patients with benign breast disease, non-users of Oral Contraceptives.Results: According to recent trials we did not observe statistically significant morphological and anatomical alterations of the breast in the group treated with estrogen-progestin therapy in comparison with the control group. Conclusion: If the woman presents a nodular breast mass during estro-progestin therapy she should be evaluated ultrasonographically to assess if the formation grows. If there is an increase in volume of the mass the patient should suspend the therapy.}, year = {2012} }
TY - JOUR T1 - Oral Contraception and Breast Diseases AU - A. Carbonaro AU - L. Ciotta AU - M. Stracquadanio AU - C. Formuso AU - M. R. Giunta AU - A. D. Agati AU - V. Leanza AU - T. T. Giannone AU - Mayada Chammas AU - Fawzi Chammas AU - C. Pafumi AU - G. Zarbo Y1 - 2012/12/30 PY - 2012 N1 - https://doi.org/10.11648/j.ajns.20120101.11 DO - 10.11648/j.ajns.20120101.11 T2 - American Journal of Nursing Science JF - American Journal of Nursing Science JO - American Journal of Nursing Science SP - 1 EP - 4 PB - Science Publishing Group SN - 2328-5753 UR - https://doi.org/10.11648/j.ajns.20120101.11 AB - Objective: Benign breast disease includes a wide spectrum of lesions different for histology and natural history, whose association with oral contraceptives is of great interest because there are no univocal results in literature. Subjects and Methods: The purpose of our study is to assess the relationship between women who used long- term estro-progestin (for at least 12 consecutive months up to a maximum of 60 months) and the develop of benign breast disease comparing with a case- control group composed by patients with benign breast disease, non-users of oral contraceptives. The study included 263 women attending, from 2009 to 2012, the Gynecological Endocrinology and Ultrasounds outpatients of our Department, who used oestroprogestative pills for Contraception, treatment of acne, hirsutism and treatment of dysmenorrheal and a control group of 200 patients with benign breast disease, non-users of Oral Contraceptives.Results: According to recent trials we did not observe statistically significant morphological and anatomical alterations of the breast in the group treated with estrogen-progestin therapy in comparison with the control group. Conclusion: If the woman presents a nodular breast mass during estro-progestin therapy she should be evaluated ultrasonographically to assess if the formation grows. If there is an increase in volume of the mass the patient should suspend the therapy. VL - 1 IS - 1 ER -