Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS)

Mohamed Kamaleldin Abdelhamid; Hosny Said Abdel Ghani; Osama Abdel Wadood Khalil; Saad El-Gelany; Nasr Mohamed Osman

doi:doi:10.11648/j.ijmi.20200802.12

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Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS)

Mohamed Kamaleldin Abdelhamid, Hosny Said Abdel Ghani, Osama Abdel Wadood Khalil, Saad El-Gelany, Nasr Mohamed Osman

Published in International Journal of Medical Imaging (Volume 8, Issue 2)

Received: 23 April 2020 Accepted: 13 May 2020 Published: 3 June 2020

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Abstract

Purpose: To evaluate the role of fetal pulmonary artery Doppler indices and quantitative ultrasound texture analysis of the fetal lung (quantus FLM) in prediction of neonatal respiratory distress syndrome. Method: This Observational prospective cross sectional study included 40 pregnant women between 28 and 40 weeks gestation. The diagnostic accuracy of MPA Doppler measurements (pulsatility index (PI), resistance index (RI) and acceleration time/ejection time (AT/ET) for diagnosis of neonatal RDS was tested by comparing the Doppler findings with the clinical outcome. Results: Of the 40 eligible fetuses, 9 (22%) developed neonatal RDS There was a significant correlation between the AT/ET and the development of the RDS as the AT/ET was significantly lower in the RDS +ve group (mean 0.27) in comparison to the RDS-ve group (mean 0.34) (P 0.001). While both PI and RI showed no statistically significant difference in between the two groups. A cutoff value of 0.3 for AT/ET predicted the development of RDS (sensitivity: 77.78%, specificity: 83.87%). Quantus FLM predicted the development of neonatal RDS with high sensitivity, specificity, positive predictive value, negative predictive value and accuracy (88.98%, 90.32%, 72.7%, 96.6% and 90%respectively). The area under curve was 0.896. Conclusion: Neonatal RDS can be predicted using the MPA AT/ET and quantitative ultrasound texture analysis of the fetal lung (quantus FLM) with high sensitivity and specificity.

Published in	International Journal of Medical Imaging (Volume 8, Issue 2)
DOI	10.11648/j.ijmi.20200802.12
Page(s)	23-34
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Fetal Lung Maturity, Neonatal Respiratory Distress Syndrome, Color Doppler Fetal Pulmonary AT/ET, Quantus FLM

References

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Mohamed Kamaleldin Abdelhamid, Hosny Said Abdel Ghani, Osama Abdel Wadood Khalil, Saad El-Gelany, Nasr Mohamed Osman. (2020). Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS). International Journal of Medical Imaging, 8(2), 23-34. https://doi.org/10.11648/j.ijmi.20200802.12

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ACS Style

Mohamed Kamaleldin Abdelhamid; Hosny Said Abdel Ghani; Osama Abdel Wadood Khalil; Saad El-Gelany; Nasr Mohamed Osman. Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS). Int. J. Med. Imaging 2020, 8(2), 23-34. doi: 10.11648/j.ijmi.20200802.12

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AMA Style

Mohamed Kamaleldin Abdelhamid, Hosny Said Abdel Ghani, Osama Abdel Wadood Khalil, Saad El-Gelany, Nasr Mohamed Osman. Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS). Int J Med Imaging. 2020;8(2):23-34. doi: 10.11648/j.ijmi.20200802.12

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@article{10.11648/j.ijmi.20200802.12,
  author = {Mohamed Kamaleldin Abdelhamid and Hosny Said Abdel Ghani and Osama Abdel Wadood Khalil and Saad El-Gelany and Nasr Mohamed Osman},
  title = {Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS)},
  journal = {International Journal of Medical Imaging},
  volume = {8},
  number = {2},
  pages = {23-34},
  doi = {10.11648/j.ijmi.20200802.12},
  url = {https://doi.org/10.11648/j.ijmi.20200802.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20200802.12},
  abstract = {Purpose: To evaluate the role of fetal pulmonary artery Doppler indices and quantitative ultrasound texture analysis of the fetal lung (quantus FLM) in prediction of neonatal respiratory distress syndrome. Method: This Observational prospective cross sectional study included 40 pregnant women between 28 and 40 weeks gestation. The diagnostic accuracy of MPA Doppler measurements (pulsatility index (PI), resistance index (RI) and acceleration time/ejection time (AT/ET) for diagnosis of neonatal RDS was tested by comparing the Doppler findings with the clinical outcome. Results: Of the 40 eligible fetuses, 9 (22%) developed neonatal RDS There was a significant correlation between the AT/ET and the development of the RDS as the AT/ET was significantly lower in the RDS +ve group (mean 0.27) in comparison to the RDS-ve group (mean 0.34) (P 0.001). While both PI and RI showed no statistically significant difference in between the two groups. A cutoff value of 0.3 for AT/ET predicted the development of RDS (sensitivity: 77.78%, specificity: 83.87%). Quantus FLM predicted the development of neonatal RDS with high sensitivity, specificity, positive predictive value, negative predictive value and accuracy (88.98%, 90.32%, 72.7%, 96.6% and 90%respectively). The area under curve was 0.896. Conclusion: Neonatal RDS can be predicted using the MPA AT/ET and quantitative ultrasound texture analysis of the fetal lung (quantus FLM) with high sensitivity and specificity.},
 year = {2020}
}

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TY  - JOUR
T1  - Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS)
AU  - Mohamed Kamaleldin Abdelhamid
AU  - Hosny Said Abdel Ghani
AU  - Osama Abdel Wadood Khalil
AU  - Saad El-Gelany
AU  - Nasr Mohamed Osman
Y1  - 2020/06/03
PY  - 2020
N1  - https://doi.org/10.11648/j.ijmi.20200802.12
DO  - 10.11648/j.ijmi.20200802.12
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 23
EP  - 34
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20200802.12
AB  - Purpose: To evaluate the role of fetal pulmonary artery Doppler indices and quantitative ultrasound texture analysis of the fetal lung (quantus FLM) in prediction of neonatal respiratory distress syndrome. Method: This Observational prospective cross sectional study included 40 pregnant women between 28 and 40 weeks gestation. The diagnostic accuracy of MPA Doppler measurements (pulsatility index (PI), resistance index (RI) and acceleration time/ejection time (AT/ET) for diagnosis of neonatal RDS was tested by comparing the Doppler findings with the clinical outcome. Results: Of the 40 eligible fetuses, 9 (22%) developed neonatal RDS There was a significant correlation between the AT/ET and the development of the RDS as the AT/ET was significantly lower in the RDS +ve group (mean 0.27) in comparison to the RDS-ve group (mean 0.34) (P 0.001). While both PI and RI showed no statistically significant difference in between the two groups. A cutoff value of 0.3 for AT/ET predicted the development of RDS (sensitivity: 77.78%, specificity: 83.87%). Quantus FLM predicted the development of neonatal RDS with high sensitivity, specificity, positive predictive value, negative predictive value and accuracy (88.98%, 90.32%, 72.7%, 96.6% and 90%respectively). The area under curve was 0.896. Conclusion: Neonatal RDS can be predicted using the MPA AT/ET and quantitative ultrasound texture analysis of the fetal lung (quantus FLM) with high sensitivity and specificity.
VL  - 8
IS  - 2
ER  -

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Author Information

Mohamed Kamaleldin Abdelhamid

Radiology Department, Faculty of Medicine, Minya University, Minya, Egypt
Hosny Said Abdel Ghani

Radiology Department, Faculty of Medicine, Minya University, Minya, Egypt
Osama Abdel Wadood Khalil

Radiology Department, Faculty of Medicine, Minya University, Minya, Egypt
Saad El-Gelany

Gyna and Obstetric Department, Faculty of Medicine, Minya University, Minya, Egypt
Nasr Mohamed Osman

Radiology Department, Faculty of Medicine, Minya University, Minya, Egypt

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Plain Text BibTeX RIS

APA Style

Mohamed Kamaleldin Abdelhamid, Hosny Said Abdel Ghani, Osama Abdel Wadood Khalil, Saad El-Gelany, Nasr Mohamed Osman. (2020). Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS). International Journal of Medical Imaging, 8(2), 23-34. https://doi.org/10.11648/j.ijmi.20200802.12

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ACS Style

Mohamed Kamaleldin Abdelhamid; Hosny Said Abdel Ghani; Osama Abdel Wadood Khalil; Saad El-Gelany; Nasr Mohamed Osman. Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS). Int. J. Med. Imaging 2020, 8(2), 23-34. doi: 10.11648/j.ijmi.20200802.12

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AMA Style

Mohamed Kamaleldin Abdelhamid, Hosny Said Abdel Ghani, Osama Abdel Wadood Khalil, Saad El-Gelany, Nasr Mohamed Osman. Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS). Int J Med Imaging. 2020;8(2):23-34. doi: 10.11648/j.ijmi.20200802.12

Copy | Download

@article{10.11648/j.ijmi.20200802.12,
  author = {Mohamed Kamaleldin Abdelhamid and Hosny Said Abdel Ghani and Osama Abdel Wadood Khalil and Saad El-Gelany and Nasr Mohamed Osman},
  title = {Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS)},
  journal = {International Journal of Medical Imaging},
  volume = {8},
  number = {2},
  pages = {23-34},
  doi = {10.11648/j.ijmi.20200802.12},
  url = {https://doi.org/10.11648/j.ijmi.20200802.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20200802.12},
  abstract = {Purpose: To evaluate the role of fetal pulmonary artery Doppler indices and quantitative ultrasound texture analysis of the fetal lung (quantus FLM) in prediction of neonatal respiratory distress syndrome. Method: This Observational prospective cross sectional study included 40 pregnant women between 28 and 40 weeks gestation. The diagnostic accuracy of MPA Doppler measurements (pulsatility index (PI), resistance index (RI) and acceleration time/ejection time (AT/ET) for diagnosis of neonatal RDS was tested by comparing the Doppler findings with the clinical outcome. Results: Of the 40 eligible fetuses, 9 (22%) developed neonatal RDS There was a significant correlation between the AT/ET and the development of the RDS as the AT/ET was significantly lower in the RDS +ve group (mean 0.27) in comparison to the RDS-ve group (mean 0.34) (P 0.001). While both PI and RI showed no statistically significant difference in between the two groups. A cutoff value of 0.3 for AT/ET predicted the development of RDS (sensitivity: 77.78%, specificity: 83.87%). Quantus FLM predicted the development of neonatal RDS with high sensitivity, specificity, positive predictive value, negative predictive value and accuracy (88.98%, 90.32%, 72.7%, 96.6% and 90%respectively). The area under curve was 0.896. Conclusion: Neonatal RDS can be predicted using the MPA AT/ET and quantitative ultrasound texture analysis of the fetal lung (quantus FLM) with high sensitivity and specificity.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Quantitative Ultrasound Texture Analysis of Fetal Lung Versus Fetal Pulmonary Artery Doppler as a Predictor of Neonatal Respiratory Distress Syndrome (RDS)
AU  - Mohamed Kamaleldin Abdelhamid
AU  - Hosny Said Abdel Ghani
AU  - Osama Abdel Wadood Khalil
AU  - Saad El-Gelany
AU  - Nasr Mohamed Osman
Y1  - 2020/06/03
PY  - 2020
N1  - https://doi.org/10.11648/j.ijmi.20200802.12
DO  - 10.11648/j.ijmi.20200802.12
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 23
EP  - 34
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20200802.12
AB  - Purpose: To evaluate the role of fetal pulmonary artery Doppler indices and quantitative ultrasound texture analysis of the fetal lung (quantus FLM) in prediction of neonatal respiratory distress syndrome. Method: This Observational prospective cross sectional study included 40 pregnant women between 28 and 40 weeks gestation. The diagnostic accuracy of MPA Doppler measurements (pulsatility index (PI), resistance index (RI) and acceleration time/ejection time (AT/ET) for diagnosis of neonatal RDS was tested by comparing the Doppler findings with the clinical outcome. Results: Of the 40 eligible fetuses, 9 (22%) developed neonatal RDS There was a significant correlation between the AT/ET and the development of the RDS as the AT/ET was significantly lower in the RDS +ve group (mean 0.27) in comparison to the RDS-ve group (mean 0.34) (P 0.001). While both PI and RI showed no statistically significant difference in between the two groups. A cutoff value of 0.3 for AT/ET predicted the development of RDS (sensitivity: 77.78%, specificity: 83.87%). Quantus FLM predicted the development of neonatal RDS with high sensitivity, specificity, positive predictive value, negative predictive value and accuracy (88.98%, 90.32%, 72.7%, 96.6% and 90%respectively). The area under curve was 0.896. Conclusion: Neonatal RDS can be predicted using the MPA AT/ET and quantitative ultrasound texture analysis of the fetal lung (quantus FLM) with high sensitivity and specificity.
VL  - 8
IS  - 2
ER  -

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