There are many treatment options available for hepatocellular carcinoma (HCC) but the best choices for intermediate and advanced tumors are sometimes a matter of controversies. The aim of the work was to compare the combined Trans-catheter arterial chemoembolization (TACE) with percutaneous ethanol injection (PEI) against the technique of TACE alone in patients with unresectable HCC. The study included fifty patients proved radiologically to have hepatocellular carcinoma (HCC) >5 cm in diameter and were not candidate for surgical resection. The patients were divided into two groups Group 1: Patients underwent single Trans-catheter arterial chemoembolization (TACE) followed by four times of Percutaneous ethanol injection (PEI) every other day. Group 2: Patients underwent repeated Trans-catheter arterial chemoembolization (the frequency of sessions was according to response of the patients). Complete resolution of HCC masses achieved in 60% in group 1 versus 52% in group 2. This complete resolution occurred earlier in group 1 than group 2. Group 1 had lower local recurrence rate than group 2. There was a statistically significant reduction in alpha-feto protein level at 3 months post interventional in group 1 and in both groups at 6 months. There was no significant difference between both groups in overall survival, So combined treatment could help in saving time and resources.
| Published in | International Journal of Medical Imaging (Volume 8, Issue 3) |
| DOI | 10.11648/j.ijmi.20200803.14 |
| Page(s) | 54-64 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2020. Published by Science Publishing Group |
Trans-catheter Arterial Chemoembolization, Percutaneous Ethanol, HCC
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APA Style
Heba Samier, Hazem Omar, Rasha Dawoud, Alsiagy Ali Salama, Abd-Elmonem Nooman. (2020). Evaluation of Combined Transcathter Arterial Chemo Embolization (TACE) with Percutaneous Ethanol Injection (PEI) Vs. (TACE) for Unresectable Hepatocellular Carcinoma. International Journal of Medical Imaging, 8(3), 54-64. https://doi.org/10.11648/j.ijmi.20200803.14
ACS Style
Heba Samier; Hazem Omar; Rasha Dawoud; Alsiagy Ali Salama; Abd-Elmonem Nooman. Evaluation of Combined Transcathter Arterial Chemo Embolization (TACE) with Percutaneous Ethanol Injection (PEI) Vs. (TACE) for Unresectable Hepatocellular Carcinoma. Int. J. Med. Imaging 2020, 8(3), 54-64. doi: 10.11648/j.ijmi.20200803.14
AMA Style
Heba Samier, Hazem Omar, Rasha Dawoud, Alsiagy Ali Salama, Abd-Elmonem Nooman. Evaluation of Combined Transcathter Arterial Chemo Embolization (TACE) with Percutaneous Ethanol Injection (PEI) Vs. (TACE) for Unresectable Hepatocellular Carcinoma. Int J Med Imaging. 2020;8(3):54-64. doi: 10.11648/j.ijmi.20200803.14
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Download@article{10.11648/j.ijmi.20200803.14,
author = {Heba Samier and Hazem Omar and Rasha Dawoud and Alsiagy Ali Salama and Abd-Elmonem Nooman},
title = {Evaluation of Combined Transcathter Arterial Chemo Embolization (TACE) with Percutaneous Ethanol Injection (PEI) Vs. (TACE) for Unresectable Hepatocellular Carcinoma},
journal = {International Journal of Medical Imaging},
volume = {8},
number = {3},
pages = {54-64},
doi = {10.11648/j.ijmi.20200803.14},
url = {https://doi.org/10.11648/j.ijmi.20200803.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20200803.14},
abstract = {There are many treatment options available for hepatocellular carcinoma (HCC) but the best choices for intermediate and advanced tumors are sometimes a matter of controversies. The aim of the work was to compare the combined Trans-catheter arterial chemoembolization (TACE) with percutaneous ethanol injection (PEI) against the technique of TACE alone in patients with unresectable HCC. The study included fifty patients proved radiologically to have hepatocellular carcinoma (HCC) >5 cm in diameter and were not candidate for surgical resection. The patients were divided into two groups Group 1: Patients underwent single Trans-catheter arterial chemoembolization (TACE) followed by four times of Percutaneous ethanol injection (PEI) every other day. Group 2: Patients underwent repeated Trans-catheter arterial chemoembolization (the frequency of sessions was according to response of the patients). Complete resolution of HCC masses achieved in 60% in group 1 versus 52% in group 2. This complete resolution occurred earlier in group 1 than group 2. Group 1 had lower local recurrence rate than group 2. There was a statistically significant reduction in alpha-feto protein level at 3 months post interventional in group 1 and in both groups at 6 months. There was no significant difference between both groups in overall survival, So combined treatment could help in saving time and resources.},
year = {2020}
}
TY - JOUR T1 - Evaluation of Combined Transcathter Arterial Chemo Embolization (TACE) with Percutaneous Ethanol Injection (PEI) Vs. (TACE) for Unresectable Hepatocellular Carcinoma AU - Heba Samier AU - Hazem Omar AU - Rasha Dawoud AU - Alsiagy Ali Salama AU - Abd-Elmonem Nooman Y1 - 2020/10/12 PY - 2020 N1 - https://doi.org/10.11648/j.ijmi.20200803.14 DO - 10.11648/j.ijmi.20200803.14 T2 - International Journal of Medical Imaging JF - International Journal of Medical Imaging JO - International Journal of Medical Imaging SP - 54 EP - 64 PB - Science Publishing Group SN - 2330-832X UR - https://doi.org/10.11648/j.ijmi.20200803.14 AB - There are many treatment options available for hepatocellular carcinoma (HCC) but the best choices for intermediate and advanced tumors are sometimes a matter of controversies. The aim of the work was to compare the combined Trans-catheter arterial chemoembolization (TACE) with percutaneous ethanol injection (PEI) against the technique of TACE alone in patients with unresectable HCC. The study included fifty patients proved radiologically to have hepatocellular carcinoma (HCC) >5 cm in diameter and were not candidate for surgical resection. The patients were divided into two groups Group 1: Patients underwent single Trans-catheter arterial chemoembolization (TACE) followed by four times of Percutaneous ethanol injection (PEI) every other day. Group 2: Patients underwent repeated Trans-catheter arterial chemoembolization (the frequency of sessions was according to response of the patients). Complete resolution of HCC masses achieved in 60% in group 1 versus 52% in group 2. This complete resolution occurred earlier in group 1 than group 2. Group 1 had lower local recurrence rate than group 2. There was a statistically significant reduction in alpha-feto protein level at 3 months post interventional in group 1 and in both groups at 6 months. There was no significant difference between both groups in overall survival, So combined treatment could help in saving time and resources. VL - 8 IS - 3 ER -
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