This research paper provides the formulation idea of herbal ultrasound gel that is of good quality. In this formulation some available chemicals and natural ingredient were used which has no harmful effect to human skin. Chemicals that used were poly acrylic acid, sodium benzoate, glycerine, food grade color, tri-ethanolamine and natural ingredient is aloe vera extract which shows effective activity against allergic, irritation and inflammation problem due to its synergistic property. Firstly, aloe gel was extracted by ethanol extraction. Gel was formulated combining all ingredients. To justify the effectiveness of any formulation, results of evaluation tests are very important. For this, necessary physicochemical properties such as appearance, transparency, consistency, homogeneity, pH, thermal stability, conductivity, spreadability, viscosity etc. were evaluated. The results were satisfactory. No microbial growth was found during the incubation period for the prepared ultrasound gel. Also, no adverse effect to the human skin like irritation, allergy, inflammation etc. was observed. Ultrasound gel usually acts as a conductive medium and the conductivity result provides the information about the image quality. Conductivity of this formulated gel was 4.05 µS/cm. Using this formulated ultrasound gel during ultrasonography, clear image was found which was also of good quality. The overall results suggest that this formulation can be considered as successful and used with no harmful effect compared to the synthetic ones.
Published in | Journal of Diseases and Medicinal Plants (Volume 6, Issue 1) |
DOI | 10.11648/j.jdmp.20200601.12 |
Page(s) | 11-15 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2020. Published by Science Publishing Group |
Ultrasonography, Poly Acrylic Acid, Aloe Vera Extract, Ultrasound Gel
[1] | Anderson MB, Eggett D. Combining topical analgesics and ultrasound - Part 2. Athletic Therapy Today. 2005, 10, 45-47. |
[2] | Cage SA, Rupp KA, Castel JC, Saliba EN, Hertel J, Saliba SA. Relative acoustic transmission of topical preparations used with therapeutic ultrasound. Archives of physical medicine and rehabilitation. 2013, 94, 2126-2130. |
[3] | Draper DO, Anderson MB. Combining topical analgesics and ultrasound - Part 1. Athletic Therapy Today. 2005, 10, 26-27. |
[4] | https://aurorapharmaceutical.com/wp-content/uploads/2012/10/Clarity-Ultrasound-Gel-v2-6-25-12.pdf. |
[5] | http://how2make.in/index.php?main_page=product_info&products_id=2500. |
[6] | http://www.premierus.com/blog/news/post/ultrasound-gel-what-it-is-and-why-we-need-it. |
[7] | Lutz H, Buscarini E and Mirk P. Basic Physics. WHO Manual of Diagnostic Ultrasound. 2nd ed. V-2, Geneva, Switzerland: World Health Organization Press; 2011, 3-4. |
[8] | Binkowski A, Riguzzi C, Price D, Fahimi J. Evaluation of a cornstarch-based ultrasound gel alternative for low-resource settings. J. Emerg. Med. 2014, 47, e5-9. |
[9] | Garcia-Miguel J, Lamas-Doménech N, Barceló-Garcia P. Allergic contact dermatitis in medical professionals due to exposure to ultrasound gel. Reumatol Clin. 2016, 12, 115-116. |
[10] | Chasset F, Soria A, Moguelet P, Mathian A, Auger Y, Francès C. Contact dermatitis due to ultrasound gel: A case report and published work review. J. Dermatol. 2016, 43, 318-320. |
[11] | Mahendran Sekar, Afikaah Sha An Ali, Ganesh Sundaram Subramanian, Vengata Subramani Manoharan, Isaac Jason J, Phan Ai Yean. Formulation and evaluation of natural ultrasound gel for physiotherapy treatment, Indo American Journal of Pharmaceutical Science, 2017, 4, 2548-2554. |
[12] | Egesie UG, Chima KE, Galam NZ. Antiinflammatory and analgesic effects of aqueous extract of Aloe vera (Aloe barbadensis) in rats. African Journal of Biomedical Research 2011, 14, 209-212. |
[13] | Asim Kumar G, Manasi B, Tapan Kumar M, Akhilesh M, Mrinal Kanti B. A study on analgesic efficacy and adverse effects of Aloe vera in wistar rats. Pharmacology online 2011, 1, 1098-1108. |
[14] | Dwivedi S, Gupta S. Formulation and evaluation of herbal gel containing Sesbania grandiflora (L) poir leaf extract. Acta Chim Pharm Indica. 2012, 2, 54-59. |
[15] | Patil S, Kadam A, Bandgar S. Formulation and evaluation of an in situ gel for ocular drug delivery of anti conjunctival drug. Cellulose Chem. Technol. 2015, 49, 35-40. |
[16] | Prasanthi D, Lakshmi PK. Optimisation of transdermal gel formulations of tolterodine tartrate by experimental design. Turk J Pharm Sci 2013, 10, 273-86. |
[17] | Bangladesh standard Specification for skin creams, BDS 1382: 2015. |
[18] | S. K. Sahoo, A. R. Samal, A. A. Mallick, S. Patra, P. C. Senapati and B. B. Barrick, Estimation and evaluation of secnidazole. The Indian Pharmacist, 2006, 5, 73-76. |
[19] | Helal DA, El-Rhman DA, Abdel-Halim SA, El Nabarawi MA. Formulation and evaluation of fluconazole topicl gel. Int J Pharm Pharm Sci. 2012, 4, 176-183. |
[20] | Shukr MH, Metwally GF. Evaluation of topical gel bases formulated with various essential oils for antibacterial activity against methicillinresistant Staphylococcus aureus. Trop. J Pharm Res. 2013, 12, 877-884. |
[21] | Khullar R, Kumar D, Seth N, Saini S. Formulation and evaluation of mefenamic acid emulgel for topical delivery. Saudi Pharm J. 2012, 20, 63-67. |
[22] | Sahu AN, Jha SB, Dubey SD. Formulation & Evaluation of Curcuminoid Based Herbal Face Cream. Indo-Global Journal of Pharmaceutical Sciences. 2011, 1, 77-84. |
[23] | Vinod KR, Santhosha D, Anbazhagan S. Formulation and evaluation of piperine creama new herbal dimensional approach for vitiligo patients. Int J Pharm Pharm Sci. 2011; 3, 29-33. |
[24] | Jagtap NS, Khadabadi SS, Farooqui IA, Nalamwar VP, Sawarkar HA. Development and evaluation of herbal wound healing formulations. Int. J. PharmTech Res. 2009, 1, 1104-1108. |
[25] | Grimm W. Extension of The International Conference on Harmonization Tripartite Guideline for Stability Testing of New Drug Substances and Products to Countries of Climatic Zones III and IV. Drug Development and Industrial Pharmacy. 1998, 24, 313- 325. |
[26] | Forster T, Rybinski WV, Wadle A. Influence of Microemulsion Phases on The Preparation Of Fine Disperse Emulsions. Adv. In Colloid & Interface Sci. 1995, 58, 119-149. |
[27] | N. MarieLode, I. Buraczewska, K. Halvarsson, Facial anti-wrinkle cream: influence of product presentation on effectiveness: a randomized and controlled study. Skin Res Technol. 2007, 13, 189–194. |
APA Style
Ferdoushi Jahan, Md. Abdul Momen, Afroza Akter Happy, Md. Hemayet Hossain, Md. Ahedul Akbor, et al. (2020). Formulation and Evaluation of Herbal Ultrasound Gel for Ultrasonography. Journal of Diseases and Medicinal Plants, 6(1), 11-15. https://doi.org/10.11648/j.jdmp.20200601.12
ACS Style
Ferdoushi Jahan; Md. Abdul Momen; Afroza Akter Happy; Md. Hemayet Hossain; Md. Ahedul Akbor, et al. Formulation and Evaluation of Herbal Ultrasound Gel for Ultrasonography. J. Dis. Med. Plants 2020, 6(1), 11-15. doi: 10.11648/j.jdmp.20200601.12
AMA Style
Ferdoushi Jahan, Md. Abdul Momen, Afroza Akter Happy, Md. Hemayet Hossain, Md. Ahedul Akbor, et al. Formulation and Evaluation of Herbal Ultrasound Gel for Ultrasonography. J Dis Med Plants. 2020;6(1):11-15. doi: 10.11648/j.jdmp.20200601.12
@article{10.11648/j.jdmp.20200601.12, author = {Ferdoushi Jahan and Md. Abdul Momen and Afroza Akter Happy and Md. Hemayet Hossain and Md. Ahedul Akbor and Sharmin Ahmed}, title = {Formulation and Evaluation of Herbal Ultrasound Gel for Ultrasonography}, journal = {Journal of Diseases and Medicinal Plants}, volume = {6}, number = {1}, pages = {11-15}, doi = {10.11648/j.jdmp.20200601.12}, url = {https://doi.org/10.11648/j.jdmp.20200601.12}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20200601.12}, abstract = {This research paper provides the formulation idea of herbal ultrasound gel that is of good quality. In this formulation some available chemicals and natural ingredient were used which has no harmful effect to human skin. Chemicals that used were poly acrylic acid, sodium benzoate, glycerine, food grade color, tri-ethanolamine and natural ingredient is aloe vera extract which shows effective activity against allergic, irritation and inflammation problem due to its synergistic property. Firstly, aloe gel was extracted by ethanol extraction. Gel was formulated combining all ingredients. To justify the effectiveness of any formulation, results of evaluation tests are very important. For this, necessary physicochemical properties such as appearance, transparency, consistency, homogeneity, pH, thermal stability, conductivity, spreadability, viscosity etc. were evaluated. The results were satisfactory. No microbial growth was found during the incubation period for the prepared ultrasound gel. Also, no adverse effect to the human skin like irritation, allergy, inflammation etc. was observed. Ultrasound gel usually acts as a conductive medium and the conductivity result provides the information about the image quality. Conductivity of this formulated gel was 4.05 µS/cm. Using this formulated ultrasound gel during ultrasonography, clear image was found which was also of good quality. The overall results suggest that this formulation can be considered as successful and used with no harmful effect compared to the synthetic ones.}, year = {2020} }
TY - JOUR T1 - Formulation and Evaluation of Herbal Ultrasound Gel for Ultrasonography AU - Ferdoushi Jahan AU - Md. Abdul Momen AU - Afroza Akter Happy AU - Md. Hemayet Hossain AU - Md. Ahedul Akbor AU - Sharmin Ahmed Y1 - 2020/01/21 PY - 2020 N1 - https://doi.org/10.11648/j.jdmp.20200601.12 DO - 10.11648/j.jdmp.20200601.12 T2 - Journal of Diseases and Medicinal Plants JF - Journal of Diseases and Medicinal Plants JO - Journal of Diseases and Medicinal Plants SP - 11 EP - 15 PB - Science Publishing Group SN - 2469-8210 UR - https://doi.org/10.11648/j.jdmp.20200601.12 AB - This research paper provides the formulation idea of herbal ultrasound gel that is of good quality. In this formulation some available chemicals and natural ingredient were used which has no harmful effect to human skin. Chemicals that used were poly acrylic acid, sodium benzoate, glycerine, food grade color, tri-ethanolamine and natural ingredient is aloe vera extract which shows effective activity against allergic, irritation and inflammation problem due to its synergistic property. Firstly, aloe gel was extracted by ethanol extraction. Gel was formulated combining all ingredients. To justify the effectiveness of any formulation, results of evaluation tests are very important. For this, necessary physicochemical properties such as appearance, transparency, consistency, homogeneity, pH, thermal stability, conductivity, spreadability, viscosity etc. were evaluated. The results were satisfactory. No microbial growth was found during the incubation period for the prepared ultrasound gel. Also, no adverse effect to the human skin like irritation, allergy, inflammation etc. was observed. Ultrasound gel usually acts as a conductive medium and the conductivity result provides the information about the image quality. Conductivity of this formulated gel was 4.05 µS/cm. Using this formulated ultrasound gel during ultrasonography, clear image was found which was also of good quality. The overall results suggest that this formulation can be considered as successful and used with no harmful effect compared to the synthetic ones. VL - 6 IS - 1 ER -